Sonja Greinacher scored 22 points as No. 21 Gonzaga, top-seeded in the West Coast Conference, easily handled eighth-seeded San Francisco 81-68 in a WCC tournament quarterfinal game.
Gonzaga faces St. Mary's in the semifinals, which defeated San Diego 60-58 on Friday.
Jazmine Redmon added 18, Lindsay Sherbert had 17, Haiden Palmer 13 and Shelby Cheslek 10 points and 10 boards as Gonzaga (27-4) shot 50 percent from the floor.
Gonzaga used a 15-4 run early in the first half, including a pair of 3-pointers by Redmon, to take an eight-point lead en route to 38-27 lead at the break.
Gonzaga led by as much as 18 early in the second half. San Francisco (12-19) cut its deficit to nine after a Taj Winston layup and Taylor Proctor 3-pointer with 6:28 to go, but the Bulldogs responded with a 7-0 run and cruised home from there.
Proctor scored 28 points to lead San Francisco. Winston finished with 15 points and seven rebounds.