TV's biggest casting changes

Published On: Jun 09 2011 01:17:17 PM PDT   Updated On: Apr 15 2014 11:00:00 PM PDT

Take a look back at some of the more memorable casting changes in the history of television.

Cheers, Rebecca, Kirstie Alley
17 / 52
Charles/Burrows/Charles Productions

She was replaced with Kirstie Alley, who played businesswoman and on-again-off-again bar manager Rebecca Howe over the show's final six seasons.

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